Dr. Kim Kultima is presenting our latest findings regarding Alzheimer’s disease at HBPP conference in Stockholm.
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder accounting for more than 50% of all dementia cases. The AD neuropathology is characterized by formation of extracellular plaques and intracellular neurofibrillary tangles consisting of aggregated amyloid-β and tau, respectively. The disease mechanism has only been partially elucidated and is believed to involve many other proteins. We have used mass spectrometry based proteomic methods to analyze the Alzheimer’s disease brain and CSF in combination with antibody based verification to increasing our knowledge in the AD neuropathology.