Clinical Analysis & Research Applying Mass spectrometry & Bioinformatics at Akademiska

GLOBAL AIM

The main focus of CARAMBA is to perform pre-clinical and clinical research, targeting endogenous and exogenous molecules, with the overall goal to improve human health care and disease prevention.

We also aim at implementing state-of-the-art as well as novel mass spectrometry and bioinformatics-based methods for use in routine clinical applications.

TEAM

Kim Kultima
Torbjörn Åkerfeldt, MD
Mats Gustaffson
Karl Sköld
Shibu Krishnan
Eva Freyhult
Stephanie Herman
Kim Kultima

Kim Kultima

Associate Professor

E-mail: [email protected]
Phone: +46 18 6114248
Website: http://katalog.uu.se/profile/?id=N2-87_2

Torbjörn Åkerfeldt, MD

Torbjörn Åkerfeldt, MD

Medical management responsible physician
Acting Section Head, Chief

E-mail: [email protected]
Phone: +46 18 6114272
Website: http://www.akademiska.se/sv/Verksamheter/Akademiska-laboratoriet/Klinisk-kemi-och-farmakologi/

Mats Gustaffson

Mats Gustaffson

Professor

Mats Gustafsson holds the first Swedish professorship in Medical Bioinformatics (2008) and is also co-director of the In vitro and systems pharmacology facility which is part of SciLifeLab. Having a strong engineering background as a former professor of signal processing at the Department of Engineering Sciences, he is currently working on new integrated experimental-computational approaches for accelerated drug development and disease understanding including biomarker identification using machine learning. These approaches are mainly related to systemic molecular profiling methods (DNA methylation, mRNA, protein, metabolite) as well as phenotypic approaches based on label free video microscopy and more specific molecular readouts. Currently the main disease areas are cancer, neurodegeneration and bacterial infections. One overarching goal is to accelerate the modelling understanding and control of biological processes involved in human diseases via phenotypic and systemic (system wide) measurements and computational analyses. Another overarching goal is to understand and resolve fundamental theoretical and computational problems of central importance in the field of Medical Bioinformatics. Currently, the efforts are mainly focused on improved computational methods to achieve better label free video microscopy monitoring of growing cell cultures, in vitro analysis & optimisation of drug combinations, in vitro systems pharmacology using different profiling techniques, and network biology approaches enabling improved molecular understanding and prediction of different disease states.

E-mail: [email protected]
Phone: +46 18 6114241
Website: http://katalog.uu.se/profile/?id=XX4146_4

Karl Sköld

Karl Sköld

Denator, Head of Research

E-mail: [email protected]
Phone: +46 18 508100
Website: http://www.denator.com

Shibu Krishnan

Shibu Krishnan

Post doc

E-mail: [email protected]
Phone: +46 18 6115959
Website: http://katalog.uu.se/profile/?id=N15-1422_1

Eva Freyhult

Eva Freyhult

Researcher/Bioinformatician

E-mail: [email protected]
Phone: +46 18 6114248
Website: http://katalog.uu.se/profile/?id=N2-1094_3

Stephanie Herman

Stephanie Herman

PhD student

With a background in bioengineering, bioinformatics and molecular biotechnology, Stephanie Herman has recently joined CARAMBA as a PhD student. Her shared focus and interests’ lies in the challenges provided by the data complexity and size of large-scale metabolomic studies and analyses of clinical metabolic data from patient diagnosed with various neurological diseases. Stephanie is part of work package 5 in the EU Horizon 2020 project PhenoMeNal, where they intend to develop a cloud-based e-infrastructure that enables scientists and health care providers to process and analyse medical metabolomics data for improved health care. Previously, Stephanie was part of the Uppsala iGEM team 2013 and project leader in the Uppsala iGEM team 2014, where she competed in the worldwide competition in Synthetic Biology hosted by Massachusetts Institute of Technology (MIT).

E-mail: [email protected]
Phone: +46 18 6115959
Website: http://katalog.uu.se/profile/?id=N15-2239_1

COLLABORATORS

PUBLICATIONS

CARAMBA members are regularly publishing in high ranked journals!

OUR PUBLICATIONS

CONTACT US

To

Your Name (required)

Your Email (required)

Subject

Your Message




Akademiska sjukhuset
Entrance 61, 3rd Floor
751 85 Uppsala
SWEDEN
————————————————–
General enquiries: [email protected]
Telephone: 018-471 00 00
————————————————–
Uppsala University, Box 256